Seminar | Manipulating Metabolism: From Cell Factories to Cancer Immunotherapy

Abstract

In its simplest sense, metabolism encompasses the incredibly diverse set of chemical reactions necessary to sustain life and allow for organismal replication. As such, the ability to manipulate and control metabolic phenotype offers wide-spread applications. Blazeck will demonstrate that by controlling metabolism in single-celled microbes, it is possible to create cellular factories that effectively produce a broad range of valuable biofuels and chemicals. He will further show that metabolic intervention in more complex mammalian hosts can target and remediate dysregulated metabolic pathways, in the process developing a novel enzymatic cancer immunotherapy.

 

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The Penn State Department of Chemical Engineering, established in 1948, is recognized as one of the largest and most influential chemical engineering departments in the nation.

The department is built upon the fundamentals of academic integrity, innovation in research, and commitment to the advancement of industry.

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